Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006509 | 0.87 | ALDH1A1 (0.45) | ALDH1A1CYP3A4MAPK1CYP2C19L3MBTL1 | |
| SCHEMBL244134 | 0.83 | CYP2D6 (0.43) | ALDH1A1CYP3A4CYP2C19L3MBTL1CA12 | |
| SCHEMBL3518969 | 0.83 | CYP2D6 (0.37) | ALDH1A1CYP3A4CYP2C19GPR119ESR1 | |
| SCHEMBL766879 | 0.82 | CA12 (0.41) | CYP3A4CYP2C19L3MBTL1CA12CA1 | |
| SCHEMBL334939 | 0.81 | ACHE (0.44) | ALDH1A1CYP3A4CYP2C19L3MBTL1POLB | |
| SCHEMBL336340 | 0.81 | ALDH1A1 (0.44) | ALDH1A1CYP3A4LMNAPOLBCA12 | |
| SCHEMBL16104743 | 0.80 | KMT2A (0.37) | ALDH1A1CYP3A4GPR119ESR1POLB | |
| SCHEMBL7026133 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP3A4LMNAPOLBCA12 | |
| SCHEMBL565372 | 0.79 | CYP2D6 (0.52) | ALDH1A1CYP3A4MAPK1CYP2C19L3MBTL1 | |
| SCHEMBL2486679 | 0.78 | CYP2D6 (0.36) | ALDH1A1GPR119ESR1ESR2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4227308-A1 | TETRAHYDROBENZOFURODIAZEPINONE COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | Japan Tobacco Inc. (JP) | 2023-08-16 | — | — | EP | disclosed |
| US-20230144411-A1 | SUBSTITUTED CYCLOHEXYL COMPOUNDS AS NOP INHIBITORS | DART NEUROSCIENCE LLC | 2023-05-11 | — | — | US | disclosed |
| US-11643417-B2 | Tetrahydrobenzofurodiazepinone compound and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2023-05-09 | — | — | US | disclosed |
| US-11643417-B2 | Tetrahydrobenzofurodiazepinone compound and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2023-05-09 | — | — | US | disclosed |
| US-20220162220-A1 | TETRAHYDROBENZOFURODIAZEPINONE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2022-05-26 | — | — | US | disclosed |
| US-8344163-B2 | Nitrile compound and its use for control of arthropod pest | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-01-01 | — | — | US | disclosed |
| US-20110021627-A1 | NITRILE COMPOUND AND ITS USE FOR CONTROL OF ARTHROPOD PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021627-A1 | NITRILE COMPOUND AND ITS USE FOR CONTROL OF ARTHROPOD PEST | C5, OR10J3, NOX3 | ALDH1A1 2305/4885CYP3A4 75/4885MAPK1 1619/4885 |
| US-11643417-B2 | Tetrahydrobenzofurodiazepinone compound and pharmaceutical use thereof | PIM1, PIM2, PIM3 | ALDH1A1 76/4885CYP3A4 92/4885MAPK1 156/4885 |
| US-20230144411-A1 | SUBSTITUTED CYCLOHEXYL COMPOUNDS AS NOP INHIBITORS | OPRL1, OPRK1, NOP56 | ALDH1A1 2958/4885CYP3A4 1905/4885MAPK1 1812/4885 |
| US-20220162220-A1 | TETRAHYDROBENZOFURODIAZEPINONE COMPOUND AND PHARMACEUTICAL USE THEREOF | PIM1, PIM2, PIM3 | ALDH1A1 76/4885CYP3A4 92/4885MAPK1 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.