Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19150035 | 0.83 | KDM1A (0.33) | TSHRKDM1AMTNR1AMTNR1BRAB9A | |
| SCHEMBL19149837 | 0.80 | TSHR (0.37) | TSHRKDM1AALDH1A1MTNR1AMTNR1B | |
| SCHEMBL4815929 | 0.77 | — | — | |
| SCHEMBL14393226 | 0.77 | RAB9A (0.43) | POLBTSHRPTGS1RAB9ASMN1; SMN2 | |
| SCHEMBL29957485 | 0.76 | KDM1A (0.39) | KDM1AMTNR1AMTNR1BRAB9ASMN1; SMN2 | |
| SCHEMBL11921771 | 0.76 | POLB (0.41) | POLBTSHRPTGS1ALDH1A1KDM4E | |
| SCHEMBL17747078 | 0.76 | NAMPT (0.35) | TSHRMTNR1AMTNR1BRAB9ASMN1; SMN2 | |
| SCHEMBL21907199 | 0.76 | MTNR1A (0.33) | TSHRKDM1AMTNR1AMTNR1BCA12 | |
| SCHEMBL18510175 | 0.75 | — | — | |
| SCHEMBL2984866 | 0.73 | MCL1 (0.44) | POLBTSHRPTGS1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230012213-A1 | NOVEL CONJUGATION CHEMISTRY FOR CATALYTIC ANTIBODY 38C2 | THE SCRIPPS RESEARCH INSTITUTE | 2023-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230012213-A1 | NOVEL CONJUGATION CHEMISTRY FOR CATALYTIC ANTIBODY 38C2 | PTMS, MRPS34, SDC2 | POLB 1622/4885TSHR 905/4885KDM1A 130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.