Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | BRAF | P15056 | 6/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24867214 | 0.85 | RAB9A (0.43) | S1PR1S1PR3RAB9AMAPK1ACACB | |
| SCHEMBL24867240 | 0.83 | BRAF (0.42) | S1PR1S1PR3RAB9AMAPK1BRAF | |
| SCHEMBL24867213 | 0.82 | TSHR (0.42) | RAB9AMAPK1ACACB | |
| SCHEMBL24867211 | 0.80 | SCN9A (0.45) | RAB9AMAPK1ACACBBRAF | |
| SCHEMBL24867210 | 0.79 | RAB9A (0.37) | S1PR1S1PR3RAB9AMAPK1ACACB | |
| SCHEMBL24867200 | 0.78 | ACACB (0.36) | RAB9AMAPK1ACACBBRAF | |
| SCHEMBL24867486 | 0.78 | RAB9A (0.44) | RAB9AMAPK1ACACB | |
| SCHEMBL24866852 | 0.78 | KDM4E (0.41) | RAB9AMAPK1 | |
| SCHEMBL24866870 | 0.77 | RAB9A (0.38) | RAB9AMAPK1ACACBBRAFKDR | |
| SCHEMBL30130213 | 0.77 | SYK (0.40) | RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283488-A9 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CZ BIOHUB SF, LLC (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023283488-A2 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CHAN ZUCKERBERG BIOHUB, INC. (US) | 2023-01-12 | — | — | WO | disclosed |