Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | VNN1 | O95497 | 8/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | ACACB | O00763 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24867202 | 0.88 | VNN1 (0.50) | RAB9AVNN1MAPK1 | |
| SCHEMBL24867208 | 0.86 | HDAC3 (0.41) | RAB9AVNN1MAPK1HDAC3HDAC1 | |
| SCHEMBL24867487 | 0.86 | HDAC3 (0.49) | RAB9AVNN1MAPK1HDAC3HDAC1 | |
| SCHEMBL24866886 | 0.86 | HDAC3 (0.41) | RAB9AVNN1MAPK1HDAC3HDAC1 | |
| SCHEMBL24867174 | 0.85 | GAA (0.49) | RAB9AMAPK1ACACBKMT2A | |
| SCHEMBL24867491 | 0.85 | GRM5 (0.43) | RAB9AMEN1KMT2A | |
| SCHEMBL24867190 | 0.85 | RAB9A (0.47) | RAB9AMAPK1HDAC3HDAC1HDAC2 | |
| SCHEMBL24866928 | 0.85 | VNN1 (0.46) | RAB9AVNN1MAPK1HDAC3HDAC1 | |
| SCHEMBL24866925 | 0.85 | VNN1 (0.46) | RAB9AVNN1MAPK1HDAC3HDAC1 | |
| SCHEMBL31159450 | 0.83 | RORC (0.48) | RAB9AMAPK1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283488-A9 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CZ BIOHUB SF, LLC (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023283488-A2 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CHAN ZUCKERBERG BIOHUB, INC. (US) | 2023-01-12 | — | — | WO | disclosed |