Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CCNK | O75909 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | LOX | P28300 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24867233 | 0.88 | CDK2 (0.43) | CDK2CCNKCCNA2CDK9MAPK1 | |
| SCHEMBL24866862 | 0.84 | HDAC3 (0.48) | CDK2MAPK1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL24867179 | 0.83 | MAPK1 (0.37) | CDK2ACACBMAPK1KDM4EPOLB | |
| SCHEMBL24867214 | 0.82 | RAB9A (0.43) | ACACBMAPK1SMN1; SMN2RAB9AKCNH3 | |
| SCHEMBL24867188 | 0.77 | EGFR (0.48) | CDK2MAPK1RAB9A | |
| SCHEMBL24867148 | 0.77 | RAB9A (0.40) | CDK2CCNA2ACACBMAPK1SMN1; SMN2 | |
| SCHEMBL24867187 | 0.76 | ACACB (0.38) | CDK2ACACBMAPK1RAB9A | |
| SCHEMBL24866885 | 0.76 | RAB9A (0.52) | CDK2CCNKCCNA2CDK9ACACB | |
| SCHEMBL24867244 | 0.76 | RAB9A (0.44) | CDK2CCNA2MAPK1KDM4EPOLB | |
| SCHEMBL30130169 | 0.76 | RAB9A (0.52) | CDK2CCNKCCNA2CDK9ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283488-A9 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CZ BIOHUB SF, LLC (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023283488-A2 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CHAN ZUCKERBERG BIOHUB, INC. (US) | 2023-01-12 | — | — | WO | disclosed |