Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 15/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24866946 | 0.89 | HDAC3 (0.41) | VNN1S1PR1S1PR3MAPK1HDAC3 | |
| SCHEMBL24867191 | 0.88 | VNN1 (0.38) | VNN1S1PR1S1PR3MAPK1HDAC3 | |
| SCHEMBL24867180 | 0.88 | VNN1 (0.43) | VNN1 | |
| SCHEMBL24866952 | 0.87 | VNN1 (0.38) | VNN1S1PR1S1PR3 | |
| SCHEMBL24867185 | 0.86 | VNN1 (0.43) | VNN1 | |
| SCHEMBL24866949 | 0.86 | VNN1 (0.41) | VNN1S1PR1S1PR3MAPK1HDAC3 | |
| SCHEMBL24866940 | 0.83 | VNN1 (0.40) | VNN1 | |
| SCHEMBL24867486 | 0.82 | RAB9A (0.44) | VNN1MAPK1HDAC3HDAC1HDAC2 | |
| SCHEMBL24867186 | 0.82 | KDM4C (0.37) | VNN1 | |
| SCHEMBL24866947 | 0.80 | VNN1 (0.35) | VNN1S1PR1S1PR3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283488-A9 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CZ BIOHUB SF, LLC (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023283488-A2 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CHAN ZUCKERBERG BIOHUB, INC. (US) | 2023-01-12 | — | — | WO | disclosed |