Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 6/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24867271 | 0.83 | SYK (0.40) | SYKNAMPTKDM4CTBK1HDAC3 | |
| SCHEMBL24866938 | 0.81 | PTK2 (0.42) | SYKNAMPT | |
| SCHEMBL24866869 | 0.79 | PDE4A (0.42) | HDAC3CDK9HDAC6 | |
| SCHEMBL24867251 | 0.75 | CHEK1 (0.39) | NAMPTHDAC3CDK9HDAC6 | |
| SCHEMBL24867253 | 0.74 | NPY5R (0.38) | NAMPTHDAC3CDK9HDAC6 | |
| SCHEMBL24867241 | 0.74 | CHEK1 (0.38) | NAMPTHDAC3CDK9HDAC6 | |
| SCHEMBL24867250 | 0.74 | CHEK1 (0.36) | TBK1JAK2HDAC3CDK9HDAC6 | |
| SCHEMBL23022184 | 0.69 | KAT2B (0.50) | TBK1 | |
| SCHEMBL763226 | 0.65 | SYK (0.73) | SYK | |
| SCHEMBL18422027 | 0.65 | MKNK1 (0.67) | KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283488-A9 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CZ BIOHUB SF, LLC (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023283488-A2 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CHAN ZUCKERBERG BIOHUB, INC. (US) | 2023-01-12 | — | — | WO | disclosed |