Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 9/20 | 0.42 |
| ▸ | ACACB | O00763 | 7/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24867303 | 0.88 | ADRB1 (0.38) | PDE4AACACBADRB1ADRB3 | |
| SCHEMBL24867300 | 0.88 | PDE4A (0.42) | PDE4AADRB1ADRB3 | |
| SCHEMBL24867490 | 0.85 | ACACB (0.43) | ACACB | |
| SCHEMBL24867299 | 0.83 | PDE4A (0.39) | PDE4AACACBADRB1ADRB3 | |
| SCHEMBL24867489 | 0.82 | CDK2 (0.38) | ACACBHDAC3HDAC1HDAC6RAB9A | |
| SCHEMBL24867301 | 0.82 | PDE4A (0.38) | PDE4AACACBADRB1ADRB3HDAC3 | |
| SCHEMBL24866886 | 0.81 | HDAC3 (0.41) | ACACBHDAC3HDAC1HDAC6RAB9A | |
| SCHEMBL24866925 | 0.80 | VNN1 (0.46) | ACACBHDAC3HDAC1HDAC6RAB9A | |
| SCHEMBL24866928 | 0.80 | VNN1 (0.46) | ACACBHDAC3HDAC1HDAC6RAB9A | |
| SCHEMBL24867208 | 0.79 | HDAC3 (0.41) | ACACBHDAC3HDAC1HDAC6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283488-A9 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CZ BIOHUB SF, LLC (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023283488-A2 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CHAN ZUCKERBERG BIOHUB, INC. (US) | 2023-01-12 | — | — | WO | disclosed |