Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10569084 | 0.84 | MEN1 (0.61) | MEN1KMT2AALOX12MAPK10RAB9A | |
| SCHEMBL24867286 | 0.81 | SCN9A (0.55) | MEN1KMT2AALOX12MAPK10KCNH2 | |
| SCHEMBL24867246 | 0.80 | AURKA (0.53) | MEN1KMT2AALOX12MAPK10RAB9A | |
| SCHEMBL24867274 | 0.79 | LTA4H (0.61) | MEN1KMT2AALOX12RAB9ANPC1 | |
| SCHEMBL30611577 | 0.78 | MEN1 (0.56) | MEN1KMT2AALOX12MAPK10RAB9A | |
| SCHEMBL14355086 | 0.77 | RAB9A (0.56) | MEN1KMT2AMAPK10RAB9ANPC1 | |
| SCHEMBL24867283 | 0.77 | AKT1 (0.40) | RAB9AMAPTLMNAMAPK1RAD52 | |
| SCHEMBL912815 | 0.76 | KMT2A (0.55) | MEN1KMT2AALOX12MAPK10RAB9A | |
| SCHEMBL3872115 | 0.76 | MEN1 (0.55) | MEN1KMT2AALOX12MAPK10RAB9A | |
| SCHEMBL24308132 | 0.76 | RAB9A (0.62) | MEN1KMT2AALOX12MAPK10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283488-A9 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CZ BIOHUB SF, LLC (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023283488-A2 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CHAN ZUCKERBERG BIOHUB, INC. (US) | 2023-01-12 | — | — | WO | disclosed |