Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20455616 | 0.82 | FFAR1 (0.40) | — | |
| SCHEMBL16959709 | 0.80 | RECQL (0.33) | RECQLTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL10105643 | 0.80 | AR (0.39) | RECQLTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL20315027 | 0.76 | RECQL (0.33) | RECQLTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL24869450 | 0.73 | EIF4A3 (0.33) | — | |
| SCHEMBL12197672 | 0.73 | CYP1A2 (0.39) | RECQLTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL15171180 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL9939598 | 0.72 | ACHE (0.35) | SLC6A2CYP1A2CYP2A6 | |
| SCHEMBL24869121 | 0.72 | MAOA (0.35) | RECQLMAOAMAOB | |
| SCHEMBL28867025 | 0.72 | KCNH2 (0.36) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023279986-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |