Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16736861 | 0.79 | LMNA (0.42) | LMNAGABRA1GABRB1PTGS2 | |
| SCHEMBL11862411 | 0.78 | LMNA (0.52) | LMNAGABRA1GABRB1TP53HTT | |
| SCHEMBL24869447 | 0.76 | EIF4A3 (0.33) | — | |
| SCHEMBL19997125 | 0.76 | LMNA (0.50) | LMNAGABRA1GABRB1 | |
| SCHEMBL24511019 | 0.74 | GABRA1 (0.41) | LMNAGABRA1GABRB1TP53HTT | |
| SCHEMBL26080932 | 0.74 | PTGDR2 (0.42) | LMNAGABRA1GABRB1TP53HTT | |
| SCHEMBL15577019 | 0.73 | CHRNB2 (0.36) | — | |
| SCHEMBL16736822 | 0.73 | LMNA (0.40) | LMNAGABRA1GABRB1 | |
| SCHEMBL20259973 | 0.73 | POLB (0.40) | HTT | |
| SCHEMBL13818324 | 0.73 | LMNA (0.48) | LMNAGABRA1GABRB1TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023279986-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |