Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13484 | 0.86 | GABRA1 (0.38) | GABRA1GABRB1EIF4A3GABRB2ADRB2 | |
| SCHEMBL12413927 | 0.86 | GABRA1 (0.38) | GABRA1GABRB1EIF4A3GABRB2ADRB2 | |
| SCHEMBL12173270 | 0.84 | EIF4A3 (0.42) | GABRA1GABRB1EIF4A3GABRB2ADRB2 | |
| SCHEMBL1335807 | 0.84 | GABRA1 (0.48) | GABRA1GABRB1GABRB2CA1CA2 | |
| SCHEMBL25796892 | 0.83 | GABRA1 (0.39) | GABRA1GABRB1EIF4A3GABRB2CA1 | |
| SCHEMBL15706603 | 0.82 | LMNA (0.38) | GABRA1GABRB1EIF4A3 | |
| SCHEMBL20686231 | 0.80 | GABRA1 (0.34) | GABRA1GABRB1EIF4A3 | |
| SCHEMBL26832324 | 0.80 | AHR (0.35) | GABRA1GABRB1EIF4A3 | |
| SCHEMBL14629520 | 0.80 | GABRA1 (0.43) | GABRA1GABRB1EIF4A3GABRB2ADRB2 | |
| SCHEMBL9194771 | 0.79 | GABRA1 (0.44) | GABRA1GABRB1GABRB2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023279986-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |