SCHEMBL24869459

SCHEMBL24869459

CC(C)c1cc(C2COC2)c(C(C)C)cc1F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.32
EIF4A3 P38919 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24869447 0.83 EIF4A3 (0.33) EIF4A3
SCHEMBL24869445 0.83 RPS6KA3 (0.36) IDH1
SCHEMBL15577019 0.73 CHRNB2 (0.36)
SCHEMBL12173270 0.73 EIF4A3 (0.42) EIF4A3
SCHEMBL15028920 0.72 TLR8 (0.35) EIF4A3
SCHEMBL25693956 0.70 CHRNB2 (0.37) IDH1
SCHEMBL25722902 0.69 HTR2A (0.30) IDH1
SCHEMBL18379738 0.69 EIF4A3 (0.40) EIF4A3
SCHEMBL1911426 0.69 EIF4A3 (0.40) EIF4A3
SCHEMBL31610743 0.68 GABRA1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023279986-A1 SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF 贝达药业股份有限公司 2023-01-12 WO disclosed