Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24869447 | 0.88 | EIF4A3 (0.33) | — | |
| SCHEMBL24869459 | 0.83 | IDH1 (0.32) | IDH1 | |
| SCHEMBL15577019 | 0.78 | CHRNB2 (0.36) | TLR9TLR8TLR7SLC6A2 | |
| SCHEMBL15028920 | 0.77 | TLR8 (0.35) | TLR9TLR8TLR7 | |
| SCHEMBL20743018 | 0.73 | MAOA (0.33) | RPS6KA3TLR9TLR8TLR7OPRL1 | |
| SCHEMBL18407477 | 0.72 | OPRL1 (0.42) | RPS6KA3TLR9TLR8TLR7OPRL1 | |
| SCHEMBL15577422 | 0.72 | RPS6KA3 (0.38) | RPS6KA3TLR9TLR8TLR7OPRL1 | |
| SCHEMBL12173270 | 0.71 | EIF4A3 (0.42) | RPS6KA3SLC6A2 | |
| SCHEMBL22156257 | 0.70 | ADRA2A (0.39) | OPRL1SOS1SLC6A2 | |
| SCHEMBL20910924 | 0.70 | PDE2A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023279986-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |