Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19341416 | 0.80 | KMT2A (0.34) | PLAUKMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL368876 | 0.77 | KMT2A (0.33) | KMT2A | |
| SCHEMBL360736 | 0.77 | HTT (0.41) | DYRK1AKMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL360056 | 0.77 | KMT2A (0.33) | KMT2AIDO1 | |
| SCHEMBL16476934 | 0.77 | SMN1; SMN2 (0.41) | DYRK1AKMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL15713825 | 0.77 | DYRK1A (0.33) | DYRK1AHTTSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2706690 | 0.74 | DYRK1A (0.34) | DYRK1AKMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24869554 | 0.73 | HDAC6 (0.34) | KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL30995460 | 0.73 | NPSR1 (0.39) | DYRK1AKMT2AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL15241061 | 0.73 | UBE2T (0.40) | DYRK1AKMT2AHTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007510-A1 | COMPOUNDS FOR BINDING AND IMAGING AMYLOID PLAQUES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-19 | — | — | WO | disclosed |