Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18720489 | 0.74 | GAA (0.42) | HTTALDH1A1GAAKDM4EHPGD | |
| SCHEMBL10169804 | 0.69 | ALDH1A1 (0.47) | HTTALDH1A1HPGDMAPTHSP90AA1 | |
| SCHEMBL12749935 | 0.69 | LMNA (0.42) | HTTALDH1A1GAAMAPTAGBL2 | |
| SCHEMBL8298570 | 0.69 | ALDH1A1 (0.43) | HTTCCR2ALDH1A1GAAKDM4E | |
| SCHEMBL13678328 | 0.68 | HTT (0.38) | HTTCCR2ALDH1A1GAAAGBL2 | |
| SCHEMBL20883735 | 0.67 | CHRM1 (0.48) | HTTALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL18720493 | 0.65 | GAA (0.42) | HTTCCR2ALDH1A1GAAKDM4E | |
| SCHEMBL10169809 | 0.65 | HSP90AA1 (0.49) | HTTALDH1A1TP53BCHEACHE | |
| SCHEMBL20883541 | 0.64 | TLR9 (0.48) | — | |
| SCHEMBL12828160 | 0.64 | PDE2A (0.40) | HTTALDH1A1GAAAGBL2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023279986-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |