Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6241138 | 0.80 | CYP1A2 (0.43) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| SCHEMBL8298121 | 0.76 | ALDH1A1 (0.33) | ALDH1A1HPGDHTTMEN1KMT2A | |
| SCHEMBL6498534 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KDM4EHPGDHTT | |
| SCHEMBL8298125 | 0.72 | AOC3 (0.33) | THRB | |
| SCHEMBL8298790 | 0.71 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KDM4EHPGDL3MBTL1 | |
| SCHEMBL24869558 | 0.69 | HTT (0.41) | ALDH1A1HSD17B10KDM4EHPGDHTT | |
| SCHEMBL6241142 | 0.66 | — | — | |
| SCHEMBL6242687 | 0.66 | CCR2 (0.33) | CCR2 | |
| SCHEMBL17712199 | 0.64 | POLB (0.47) | ALDH1A1HSD17B10KDM4EHPGDHTT | |
| SCHEMBL29509457 | 0.64 | POLB (0.47) | ALDH1A1HSD17B10KDM4EHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |