Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 8/20 | 0.69 |
| ▸ | DRD2 | P14416 | 6/20 | 0.69 |
| ▸ | DRD5 | P21918 | 6/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 4/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2569339 | 0.93 | DRD1 (0.73) | DRD1DRD2DRD5KDM4EMEN1 | |
| SCHEMBL6247473 | 0.87 | DRD2 (0.62) | DRD1DRD2DRD5MAOAMAOB | |
| SCHEMBL30897518 | 0.87 | ALDH1A1 (0.54) | DRD1DRD2DRD5KDM4EMEN1 | |
| Bromide SCHEMBL20854693 | 0.85 | DRD2 (0.66) | DRD1DRD2DRD5KDM4EMAPT | |
| SCHEMBL24073822 | 0.80 | MAOA (0.53) | DRD1DRD2DRD5MAOAMAOB | |
| SCHEMBL25557887 | 0.80 | MAOA (0.53) | DRD1DRD2DRD5MAOAMAOB | |
| SCHEMBL31260373 | 0.79 | MAOA (0.51) | DRD1DRD2DRD5MAOAMAOB | |
| SCHEMBL29573217 | 0.79 | MAOA (0.51) | DRD1DRD2DRD5MAOAMAOB | |
| SCHEMBL29572411 | 0.79 | MAOA (0.51) | DRD1DRD2DRD5MAOAMAOB | |
| SCHEMBL12826670 | 0.79 | MAOA (0.51) | DRD1DRD2DRD5MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023281417-A1 | PYRIMIDINE COMPOUNDS FOR USE AS MAP4K1 INHIBITORS | GLENMARK SPECIALTY S.A. (CH) | 2023-01-12 | — | — | WO | disclosed |