Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3254360 | 0.86 | KMT2A (0.44) | KMT2AHRH3GAAMGAMSI | |
| SCHEMBL24870453 | 0.85 | KMT2A (0.40) | KMT2AHRH3HTR4HRH1ALDH1A1 | |
| SCHEMBL21070287 | 0.84 | ALDH1A1 (0.40) | KMT2AHRH3GAAALDH1A1TSHR | |
| SCHEMBL3248118 | 0.83 | KMT2A (0.49) | KMT2AHRH3GAAMGAMSI | |
| SCHEMBL3264372 | 0.81 | KMT2A (0.47) | KMT2AHRH3GAAMGAMSI | |
| SCHEMBL12617901 | 0.81 | KMT2A (0.41) | KMT2ANCF1GNAI3GNAO1GNAI1 | |
| SCHEMBL22564949 | 0.80 | NCF1 (0.41) | HTR4NCF1GNAI3GNAO1GNAI1 | |
| SCHEMBL2607204 | 0.80 | NCF1 (0.41) | KMT2ANCF1GNAI3GNAO1GNAI1 | |
| SCHEMBL3387696 | 0.79 | TSHR (0.41) | KMT2AHRH3GAAMGAMSI | |
| SCHEMBL6517420 | 0.79 | PLG (0.39) | KMT2AHRH3GAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280026-A1 | HETEROAROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-01-12 | — | — | WO | disclosed |