Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6081935 | 0.91 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1NPSR1LMNAKMT2A | |
| SCHEMBL8329591 | 0.90 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1NPSR1LMNAKMT2A | |
| SCHEMBL9209640 | 0.86 | L3MBTL1 (0.61) | ALDH1A1L3MBTL1NPSR1LMNAKMT2A | |
| SCHEMBL1565359 | 0.83 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1NPSR1LMNAKMT2A | |
| SCHEMBL31547177 | 0.83 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1NPSR1LMNAKMT2A | |
| SCHEMBL9451713 | 0.82 | L3MBTL1 (0.58) | ALDH1A1L3MBTL1NPSR1LMNAKMT2A | |
| SCHEMBL334541 | 0.82 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1NPSR1KMT2ATSHR | |
| SCHEMBL1616497 | 0.81 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1NPSR1LMNAKMT2A | |
| SCHEMBL1565504 | 0.81 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1NPSR1LMNAKMT2A | |
| SCHEMBL2078533 | 0.81 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1NPSR1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4366835-A1 | HETEROCYCLOALKYL AND HETEROARYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT MODULATE IKZF2 | Plexium, Inc. (US) | 2024-05-15 | — | — | EP | disclosed |
| WO-2023283428-A1 | HETEROCYCLOALKYL AND HETEROARYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT MODULATE IKZF2 | Plexium, Inc. (US) | 2023-01-12 | — | — | WO | disclosed |
| WO-2023283428-A1 | HETEROCYCLOALKYL AND HETEROARYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT MODULATE IKZF2 | Plexium, Inc. (US) | 2023-01-12 | — | — | WO | disclosed |