Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24869876 | 0.90 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1NPSR1KMT2ALMNA | |
| SCHEMBL6081935 | 0.85 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1NPSR1KMT2ALMNA | |
| SCHEMBL8330056 | 0.83 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1NPSR1KMT2ATSHR | |
| SCHEMBL1565359 | 0.77 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1NPSR1KMT2ALMNA | |
| SCHEMBL31547177 | 0.77 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1NPSR1KMT2ALMNA | |
| SCHEMBL1565504 | 0.76 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1NPSR1KMT2ALMNA | |
| SCHEMBL1616497 | 0.76 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1NPSR1KMT2ALMNA | |
| SCHEMBL2078533 | 0.76 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1NPSR1KMT2ALMNA | |
| SCHEMBL9209640 | 0.76 | L3MBTL1 (0.61) | ALDH1A1L3MBTL1NPSR1KMT2ALMNA | |
| SCHEMBL8329599 | 0.74 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1NPSR1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |