Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 3/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20342557 | 0.80 | HDAC4 (0.48) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL30824474 | 0.77 | ALDH1A1 (0.47) | HTR3AHRH4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28695999 | 0.77 | HDAC4 (0.43) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL29835415 | 0.75 | PDE10A (0.41) | HTR3AHRH4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29184273 | 0.75 | L3MBTL1 (0.45) | NPC1RAB9ASMN1; SMN2KDM4EPDE10A | |
| SCHEMBL24290202 | 0.74 | HTR3A (0.41) | HTR3AHRH4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4305890 | 0.73 | SLC6A2 (0.55) | — | |
| SCHEMBL29590357 | 0.72 | MEN1 (0.55) | HRH4NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3703819 | 0.72 | MEN1 (0.55) | HRH4NPC1RAB9ASMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL3709193 | 0.71 | MEN1 (0.54) | HRH4NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283428-A1 | HETEROCYCLOALKYL AND HETEROARYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT MODULATE IKZF2 | Plexium, Inc. (US) | 2023-01-12 | — | — | WO | disclosed |