Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | DNM2 | P50570 | 6/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933366 | 0.82 | NPC1 (0.43) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27208121 | 0.82 | TERT (0.46) | TERTHTTSIGMAR1 | |
| SCHEMBL201692 | 0.78 | NPC1 (0.57) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL19259251 | 0.77 | HPGD (0.40) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL6066009 | 0.77 | SLC6A4 (0.44) | SIGMAR1 | |
| SCHEMBL27977349 | 0.77 | NPC1 (0.55) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL28031372 | 0.77 | NPC1 (0.55) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL28215541 | 0.77 | NPC1 (0.55) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL2230538 | 0.76 | TERT (0.49) | TERTSIGMAR1DNM2 | |
| SCHEMBL10633892 | 0.75 | SIGMAR1 (0.48) | PTGS2CYP3A4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283473-A1 | POLY(DIALKYL BETA-LACTONE) COMPOSITIONS, METHODS OF MAKING SAME AND USES THEREOF | CORNELL UNIVERSITY (US) | 2023-01-12 | — | — | WO | disclosed |