Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 4/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.37 |
| ▸ | NPY4R | P50391 | 4/20 | 0.37 |
| ▸ | NPY1R | P25929 | 3/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14978855 | 0.89 | NMT2 (0.45) | FURINNPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL15692124 | 0.89 | NMT2 (0.45) | FURINNPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL23355149 | 0.89 | CTSL (0.42) | FURINNPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL24270749 | 0.88 | FURIN (0.43) | FURINHTT | |
| SCHEMBL20839656 | 0.88 | NPY5R (0.42) | FURINNPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL17312902 | 0.88 | FURIN (0.41) | FURINNPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL21607790 | 0.87 | FURIN (0.42) | FURINNPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL26223125 | 0.87 | FURIN (0.42) | FURINNPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL20729885 | 0.86 | HTT (0.39) | FURINHTTSMN1; SMN2KMT2A | |
| SCHEMBL23943639 | 0.86 | FURIN (0.44) | FURINNPY5RNPY4RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283595-A2 | INTEGRIN TARGETING LIGANDS FOR OCULAR DELIVERY OF RNAI COMPOUNDS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-01-12 | — | — | WO | disclosed |