SCHEMBL24873138

SCHEMBL24873138

N#CC(C#N)=C1c2cc(Br)ccc2-c2nc(C#N)c(C#N)nc21

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 9/20 0.48
USP47 Q96K76 4/20 0.48
USP8 P40818 17/20 0.41
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
PKM P14618 1/20 0.34
ERBB2 P04626 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10074368 0.80 USP8 (0.57) USP7USP47USP8
SCHEMBL29548811 0.80 USP8 (0.57) USP7USP47USP8
SCHEMBL11960739 0.77 MAPT (0.51) ALDH1A1GAAMAPTPKM
SCHEMBL24873135 0.77 USP7 (0.72) USP7USP47USP8
SCHEMBL24872860 0.74 USP7 (0.38) USP7USP47USP8
SCHEMBL24872859 0.74 USP8 (0.45) USP7USP47USP8ALDH1A1GAA
SCHEMBL10074709 0.73 USP8 (0.39) USP7USP47USP8
SCHEMBL10074369 0.73 USP8 (0.49) USP7USP47USP8
SCHEMBL10074708 0.72 USP8 (0.47) USP7USP47USP8ALDH1A1ERBB2
SCHEMBL10074715 0.72 USP8 (0.50) USP7USP47USP8ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023282128-A1 HOLE TRANSPORT PROMOTING MATERIAL, MATERIAL FOR LIGHT RECEIVING ELEMENT, CYANO COMPOUND, AND ORGANIC LIGHT RECEIVING ELEMENT 東ソー株式会社 2023-01-12 WO disclosed