SCHEMBL10074368

SCHEMBL10074368

N#CC(C#N)=C1c2ccccc2-c2nc(C#N)c(C#N)nc21

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
USP8 P40818 19/20 0.57
USP7 Q93009 8/20 0.57
USP47 Q96K76 4/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29548811 1.00 USP8 (0.57) USP8USP7USP47
SCHEMBL10074369 0.92 USP8 (0.49) USP8USP7USP47
SCHEMBL19114663 0.89 USP8 (0.42) USP8USP7USP47
SCHEMBL2756401 0.83 ALDH1A1 (0.38) USP8USP7USP47
SCHEMBL1754982 0.83 ALDH1A1 (0.38) USP8USP7USP47
SCHEMBL24872857 0.81 ALDH1A1 (0.47) USP8USP7USP47
SCHEMBL24872859 0.80 USP8 (0.45) USP8USP7USP47
SCHEMBL24422411 0.80 USP8 (0.36) USP8USP7USP47
SCHEMBL24873138 0.80 USP7 (0.48) USP8USP7USP47
SCHEMBL10074517 0.80 USP8 (0.40) USP8USP7USP47

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114349680-A Organic piezoelectric composite material and preparation and application thereof 南京邮电大学 2022-04-15 CN claimed
WO-2023282128-A1 HOLE TRANSPORT PROMOTING MATERIAL, MATERIAL FOR LIGHT RECEIVING ELEMENT, CYANO COMPOUND, AND ORGANIC LIGHT RECEIVING ELEMENT 東ソー株式会社 2023-01-12 WO disclosed
CN-114349680-A Organic piezoelectric composite material and preparation and application thereof 南京邮电大学 2022-04-15 CN disclosed
CN-114349680-A Organic piezoelectric composite material and preparation and application thereof 南京邮电大学 2022-04-15 CN disclosed
CN-112724090-A Electron-deficient azafluorene organic heterojunction material and preparation method and application thereof 南京工业大学 2021-04-30 CN disclosed
US-8119828-B2 Material for an organic electroluminescence device and an organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2012-02-21 US disclosed
US-20100044686-A1 MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100044686-A1 MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE AFF4, KCNH3, HCN4 USP8 4307/4885USP7 4265/4885USP47 4258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.