SCHEMBL10074369

SCHEMBL10074369

N#CC(C#N)=C1c2ccccc2-c2nc3nc(C#N)c(C#N)nc3nc21

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
USP8 P40818 18/20 0.49
USP7 Q93009 7/20 0.49
USP47 Q96K76 4/20 0.49
GPR35 Q9HC97 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10074368 0.92 USP8 (0.57) USP8USP7USP47
SCHEMBL29548811 0.92 USP8 (0.57) USP8USP7USP47
SCHEMBL19114663 0.85 USP8 (0.42) USP8USP7USP47GPR35
SCHEMBL10050459 0.81 USP8 (0.43) USP8USP7USP47
SCHEMBL2756401 0.79 ALDH1A1 (0.38) USP8USP7USP47GPR35
SCHEMBL1754982 0.79 ALDH1A1 (0.38) USP8USP7USP47GPR35
SCHEMBL24872857 0.77 ALDH1A1 (0.47) USP8USP7USP47GPR35
SCHEMBL24422411 0.76 USP8 (0.36) USP8USP7USP47GPR35
SCHEMBL10075458 0.76 MAOB (0.42) USP8USP7USP47
SCHEMBL10050483 0.76 USP8 (0.83) USP8USP7USP47

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023282128-A1 HOLE TRANSPORT PROMOTING MATERIAL, MATERIAL FOR LIGHT RECEIVING ELEMENT, CYANO COMPOUND, AND ORGANIC LIGHT RECEIVING ELEMENT 東ソー株式会社 2023-01-12 WO disclosed
US-8119828-B2 Material for an organic electroluminescence device and an organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2012-02-21 US disclosed
US-20100044686-A1 MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100044686-A1 MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE AFF4, KCNH3, HCN4 USP8 4307/4885USP7 4265/4885USP47 4258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.