Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP8 | P40818 | 9/20 | 0.39 |
| ▸ | USP7 | Q93009 | 8/20 | 0.39 |
| ▸ | USP47 | Q96K76 | 4/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10074708 | 0.88 | USP8 (0.47) | USP8USP7USP47PGR | |
| SCHEMBL10074715 | 0.88 | USP8 (0.50) | USP8USP7USP47 | |
| SCHEMBL19114900 | 0.87 | PDK2 (0.40) | PDK2MMP3MAP4K4PARP1PGR | |
| SCHEMBL20930524 | 0.78 | MMP3 (0.44) | PDK2MMP3MAP4K4PGRKIF11 | |
| SCHEMBL10074511 | 0.78 | PDK2 (0.43) | PDK2MMP3MAP4K4PARP1GABRA1 | |
| SCHEMBL10075474 | 0.78 | HSD17B1 (0.38) | USP8USP7USP47 | |
| SCHEMBL10075457 | 0.78 | MMP3 (0.47) | PDK2MMP3MAP4K4PGRKIF11 | |
| SCHEMBL29548811 | 0.76 | USP8 (0.57) | USP8USP7USP47 | |
| SCHEMBL10074368 | 0.76 | USP8 (0.57) | USP8USP7USP47 | |
| SCHEMBL20930817 | 0.76 | MMP3 (0.46) | PDK2MMP3MAP4K4PGRKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119828-B2 | Material for an organic electroluminescence device and an organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20100044686-A1 | MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100044686-A1 | MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE | AFF4, KCNH3, HCN4 | USP8 4307/4885USP7 4265/4885USP47 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.