Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 4/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.37 |
| ▸ | DNPEP | Q9ULA0 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21696331 | 0.84 | RAB9A (0.38) | ANPEPRNPEPDNPEPSMN1; SMN2RAB9A | |
| SCHEMBL21763558 | 0.84 | ANPEP (0.40) | ANPEPRNPEPDNPEPSMN1; SMN2RAB9A | |
| SCHEMBL23734275 | 0.78 | ANPEP (0.41) | ANPEPRNPEPDNPEPSMN1; SMN2RAB9A | |
| SCHEMBL23299774 | 0.77 | CYP1A2 (0.33) | CYP1A2 | |
| SCHEMBL18893563 | 0.77 | CYP1A2 (0.39) | CYP1A2 | |
| SCHEMBL22385106 | 0.76 | CYP1A2 (0.36) | CYP1A2 | |
| SCHEMBL12015001 | 0.75 | ANPEP (0.44) | ANPEPRNPEPDNPEPSMN1; SMN2RAB9A | |
| SCHEMBL24913301 | 0.75 | CNR1 (0.40) | ANPEPRNPEPDNPEPSMN1; SMN2RAB9A | |
| SCHEMBL21030119 | 0.74 | CYP1A2 (0.35) | CYP1A2MMP2MMP8 | |
| SCHEMBL18287157 | 0.72 | ANPEP (0.42) | ANPEPRNPEPDNPEPSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023281485-A1 | MODIFIED IL-2 POLYPEPTIDES FOR TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES | BRIGHT PEAK THERAPEUTICS AG (CH) | 2023-01-12 | — | — | WO | disclosed |