Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | ANPEP | P15144 | 4/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23734275 | 0.85 | ANPEP (0.41) | CNR1ANPEPRNPEPDNPEPSMN1; SMN2 | |
| SCHEMBL21763558 | 0.79 | ANPEP (0.40) | CNR1ANPEPRNPEPDNPEPSMN1; SMN2 | |
| SCHEMBL24126081 | 0.79 | CNR1 (0.43) | CNR1SMN1; SMN2HSD17B10 | |
| SCHEMBL19509788 | 0.79 | CNR1 (0.50) | CNR1MMP2 | |
| SCHEMBL12015001 | 0.78 | ANPEP (0.44) | CNR1ANPEPRNPEPDNPEPSMN1; SMN2 | |
| SCHEMBL21696331 | 0.76 | RAB9A (0.38) | CNR1ANPEPRNPEPDNPEPSMN1; SMN2 | |
| SCHEMBL17447468 | 0.76 | CCR2 (0.39) | CNR1ANPEPRNPEPDNPEPL3MBTL1 | |
| SCHEMBL24678335 | 0.76 | CNR1 (0.55) | CNR1MMP2 | |
| SCHEMBL24873174 | 0.75 | ANPEP (0.37) | CNR1ANPEPRNPEPDNPEPSMN1; SMN2 | |
| SCHEMBL1310832 | 0.75 | ANPEP (0.46) | CNR1ANPEPRNPEPDNPEPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230028321-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230028321-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | POLRMT, NSUN2, NUDT1 | CNR1 3543/4885ANPEP 1229/4885RNPEP 556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.