Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 4/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.40 |
| ▸ | DNPEP | Q9ULA0 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21696331 | 0.85 | RAB9A (0.38) | ANPEPRNPEPDNPEPSMN1; SMN2RAB9A | |
| SCHEMBL24873174 | 0.84 | ANPEP (0.37) | ANPEPRNPEPDNPEPSMN1; SMN2RAB9A | |
| SCHEMBL23734275 | 0.82 | ANPEP (0.41) | ANPEPRNPEPDNPEPSMN1; SMN2RAB9A | |
| SCHEMBL23618234 | 0.80 | CYP2D6 (0.46) | GAAHSD17B10CNR1CNR2MMP8 | |
| SCHEMBL12015001 | 0.79 | ANPEP (0.44) | ANPEPRNPEPDNPEPSMN1; SMN2RAB9A | |
| SCHEMBL24913301 | 0.79 | CNR1 (0.40) | ANPEPRNPEPDNPEPSMN1; SMN2RAB9A | |
| SCHEMBL21946461 | 0.78 | KDM4C (0.42) | SMN1; SMN2GAACNR1MMP2MEN1 | |
| SCHEMBL12180236 | 0.78 | CNR1 (0.44) | SMN1; SMN2CNR1MEN1KMT2AMAPT | |
| SCHEMBL21664380 | 0.76 | CNR1 (0.31) | CNR1CNR2 | |
| SCHEMBL17178022 | 0.76 | ALDH1A1 (0.31) | SMN1; SMN2CNR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200064357-A1 | METHODS FOR DETERMINING AND MONITORING GASTROINTESTINAL INFLAMMATION | PROTAGONIST THERAPEUTICS, INC. | 2020-02-27 | — | — | US | disclosed |