⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1630364 | 0.54 | — | — | |
| SCHEMBL4704406 | 0.53 | — | — | |
| SCHEMBL16289065 | 0.53 | — | — | |
| SCHEMBL17103386 | 0.53 | — | — | |
| SCHEMBL3128585 | 0.53 | — | — | |
| SCHEMBL449374 | 0.53 | — | — | |
| SCHEMBL19122064 | 0.51 | — | — | |
| SCHEMBL662302 | 0.48 | PGK1 (0.38) | — | |
| Bromide SCHEMBL9813321 | 0.46 | NOTUM (0.37) | — | |
| SCHEMBL1538924 | 0.45 | GABRA1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380898-B1 | Process to make glucocorticoid compounds | GLAXO GROUP LTD (GB) | 2013-08-28 | — | — | EP | claimed |
| EP-1644398-B1 | SPECIFIC GLUCOCORTICOSTEROID COMPOUND HAVING ANTI- INFLAMMATORY ACTIVITY | GLAXO GROUP LTD (GB) | 2013-01-09 | — | — | EP | claimed |
| EP-2380898-A1 | Process to make glucocortisoid compounds | GLAXO GROUP LIMITED (GB) | 2011-10-26 | — | — | EP | claimed |
| US-20070149600-A1 | Substituted octahydroisoindoles | BIOVITRUM AB (SE) | 2007-06-28 | — | — | US | claimed |
| WO-2006114402-A1 | SUBSTITUTED OCTAHYDROISOINDOLES AS ANTAGONISTS OF MELANIN CONCENTRATING HORMONE RECEPTOR 1 (MCH1R) | BIOVITRUM AB (PUBL) (SE) | 2006-11-02 | — | — | WO | claimed |
| CN-108477173-B | Heterocyclic compounds as pesticides | 拜耳农作物科学股份公司 | 2021-07-02 | — | — | CN | disclosed |
| US-10435374-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2019-10-08 | — | — | US | disclosed |
| CN-108477173-A | Heterocyclic compound as insecticide | 拜耳农作物科学股份公司 | 2018-09-04 | — | — | CN | disclosed |
| US-9955689-B2 | Method for promoting plant growth | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-05-01 | — | — | US | disclosed |
| CN-105101800-B | Heterocyclic Compounds as Pesticides | 拜耳农作物科学股份公司 | 2018-04-13 | — | — | CN | disclosed |
| US-9894901-B2 | Method for promoting plant growth | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-02-20 | — | — | US | disclosed |
| US-9872493-B2 | Method for promoting plant growth | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-01-23 | — | — | US | disclosed |
| US-20080070880-A1 | SPECIFIC GLUCOCORTICOSTEROID COMPOUND HAVING ANTI-INFLAMMATORY ACTIVITY | BIGGADIKE KEITH | 2008-03-20 | — | — | US | disclosed |
| US-20080021231-A1 | Novel compounds | BIGGADIKE KEITH | 2008-01-24 | — | — | US | disclosed |
| US-20080015360-A1 | Novel compounds | JOHN MATTHEW P | 2008-01-17 | — | — | US | disclosed |
| US-7288536-B2 | Specific glucocorticosteroid compound having anti-inflammatory activity | GLAXO GROUP LIMITED (GB) | 2007-10-30 | — | — | US | disclosed |
| US-20070149600-A1 | Substituted octahydroisoindoles | BIOVITRUM AB (SE) | 2007-06-28 | — | — | US | disclosed |
| US-20060247219-A1 | Specific glucocorticosteriod compound having anti-inflamatory activity | GLAXO GROUP LIMITED (GB) | 2006-11-02 | — | — | US | disclosed |
| EP-1644398-A1 | SPECIFIC GLUCOCORTICOSTEROID COMPOUND HAVING ANTI- INFLAMMATORY ACTIVITY | GLAXO GROUP LIMITED (GB) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005005451-A1 | SPECIFIC GLUCOCORTICOSTEROID COMPOUND HAVING ANTI- INFLAMMATORY ACTIVITY | GLAXO GROUP LIMITED (GB) | 2005-01-20 | — | — | WO | disclosed |