Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | PARG | Q86W56 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1535572 | 0.76 | TDP1 (0.40) | ROCK2POLBADORA1TMIGD3CCNE2 | |
| SCHEMBL20241760 | 0.74 | POLB (0.38) | ROCK2POLBADORA1TMIGD3CCNE2 | |
| SCHEMBL934741 | 0.73 | PDE10A (0.43) | — | |
| SCHEMBL2484820 | 0.68 | PDE2A (0.41) | PDE2A | |
| SCHEMBL2469161 | 0.68 | TDP1 (0.34) | — | |
| SCHEMBL2464647 | 0.68 | PDE10A (0.42) | — | |
| SCHEMBL2465756 | 0.66 | POLB (0.38) | POLBALDH1A1HPGDNPSR1 | |
| SCHEMBL3028035 | 0.65 | ROCK2 (0.35) | ROCK2POLBADORA1PDE2APARP1 | |
| SCHEMBL985480 | 0.65 | TDP1 (0.53) | — | |
| SCHEMBL2469819 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694651-B1 | HERBICIDAL PYRIMIDINES | DU PONT (US) | 2011-10-19 | — | — | EP | claimed |