SCHEMBL985480

SCHEMBL985480

Nc1c(Cl)c(Cl)nc(OC(=O)O)c1Cl

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.53
MAPT P10636 2/20 0.39
ATM Q13315 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2469161 0.80 TDP1 (0.34) TDP1
SCHEMBL8761857 0.77 TDP1 (0.49) TDP1MAPTATML3MBTL1LMNA
SCHEMBL8785168 0.76 TDP1 (0.34) TDP1LMNAGAA
SCHEMBL2467803 0.75 ALDH1A1 (0.46) MAPTLMNAGAA
SCHEMBL2465144 0.74 KDM4E (0.39) TDP1MAPTL3MBTL1LMNAGAA
SCHEMBL23967663 0.74 TDP1 (0.46) TDP1MAPTATML3MBTL1LMNA
SCHEMBL22183888 0.74 TDP1 (0.46) TDP1MAPTATML3MBTL1LMNA
SCHEMBL2469819 0.73
SCHEMBL934741 0.72 PDE10A (0.43)
SCHEMBL19356871 0.71 MEN1 (0.33) MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1429612-A1 HERBICIDES CONTAINING SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONE Bayer CropScience AG (DE) 2004-06-23 EP claimed
EP-1372395-A1 HERBICIDES BASED ON SUBSTITUTED ARYL KETONES Bayer CropScience AG (DE) 2004-01-02 EP claimed
WO-2003026426-A1 HERBICIDES CONTAINING SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONE BAYER CROPSCIENCE AG (DE) 2003-04-03 WO claimed
WO-2003000058-A1 SELECTIVE HERBICIDES BASED ON PYRIMIDINE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2003-01-03 WO claimed
WO-2002071845-A1 HERBICIDES BASED ON SUBSTITUTED ARYL KETONES BAYER CROPSCIENCE AG (DE) 2002-09-19 WO claimed
EP-1233672-A2 SYNERGISTIC HERBICIDAL ACTIVE SUBSTANCE COMBINATIONS Bayer Aktiengesellschaft (DE) 2002-08-28 EP claimed
EP-1221848-A1 SELECTIVE HERBICIDES ON THE BASIS OF N-ARYL-TRIAZOLINE(THI)ONES Bayer Aktiengesellschaft (DE) 2002-07-17 EP claimed
WO-2001035741-A2 SYNERGISTIC HERBICIDAL ACTIVE SUBSTANCE COMBINATIONS BAYER AKTIENGESELLSCHAFT (DE) 2001-05-25 WO claimed
EP-0843666-B1 4-SUBSTITUTED 5-POLYCYCLYLPYRIMIDINE HERBICIDES DOW AGROSCIENCES LLC (US) 2001-05-16 EP claimed
WO-2001022819-A1 SELECTIVE HERBICIDES ON THE BASIS OF N-ARYL-TRIAZOLINE(THI)ONES BAYER AKTIENGESELLSCHAFT (DE) 2001-04-05 WO claimed
EP-0553074-B1 METHOD AND COMPOSITION FOR ENHANCING UPTAKE AND TRANSPORT OF BIOACTIVE AGENTS IN PLANTS TOMEN CORP (JP) 1996-06-05 EP claimed
EP-0469406-B1 Herbicidal compositions IDEMITSU KOSAN CO (JP) 1996-01-17 EP claimed
EP-0496608-B1 Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same ISHIHARA SANGYO KAISHA (JP) 1995-09-20 EP claimed
EP-0141373-B1 DELIVERY SYSTEM FOR MERISTEMATIC TISSUE PLANT GENETICS, INC. (US) 1991-10-16 EP claimed
EP-2091332-B1 HERBICIDAL COMBINATIONS COMPRISING AMIDOSULFURON AND A PYRIDINE-HERBICIDE BAYER IP GMBH (DE) 2016-05-18 EP disclosed
EP-2301352-A1 Herbicide based on substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)ones and dimethamid Bayer CropScience AG (DE) 2011-03-30 EP disclosed
EP-2279663-A2 Herbicides based on substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)ones and mesotrione Bayer CropScience Aktiengesellschaft (DE) 2011-02-02 EP disclosed
EP-0507171-A1 Sulfonylaminocarbonyltriazolinones with oxygen-bound substituents BAYER AG (DE) 1992-10-07 EP disclosed
EP-0419831-A2 Substituted sulfonylaminoazoles BAYER AG (DE) 1991-04-03 EP disclosed
EP-0330959-A2 Substituted sulphonyl amino azoles BAYER AG (DE) 1989-09-06 EP disclosed