SCHEMBL2469161

SCHEMBL2469161

Nc1c(Cl)c(OC(=O)O)nc(C2CC2)c1Cl

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2469819 0.87
SCHEMBL985480 0.80 TDP1 (0.53) TDP1
SCHEMBL2469159 0.76 TDP1 (0.58) TDP1
SCHEMBL2464647 0.75 PDE10A (0.42)
SCHEMBL2465756 0.73 POLB (0.38)
SCHEMBL934741 0.71 PDE10A (0.43)
SCHEMBL2463927 0.71 NPSR1 (0.40) TDP1
SCHEMBL2487474 0.68 ROCK2 (0.35)
SCHEMBL2467803 0.68 ALDH1A1 (0.46)
SCHEMBL2465144 0.67 KDM4E (0.39) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2369927-A2 HERBICIDE-SAFENER COMBINATION Bayer CropScience AG (DE) 2011-10-05 EP claimed
WO-2010060579-A2 HERBICIDE-SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 WO claimed
EP-2369927-A2 HERBICIDE-SAFENER COMBINATION Bayer CropScience AG (DE) 2011-10-05 EP disclosed
EP-2210492-A1 Herbicide safener combination Bayer CropScience AG (DE) 2010-07-28 EP disclosed
WO-2010060579-A2 HERBICIDE-SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 WO disclosed