⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24874192 | 0.85 | — | — | |
| SCHEMBL24253397 | 0.71 | LMNA (0.42) | — | |
| SCHEMBL22455689 | 0.66 | LMNA (0.42) | — | |
| SCHEMBL25883784 | 0.64 | — | — | |
| SCHEMBL16744195 | 0.61 | TRPM5 (0.31) | — | |
| SCHEMBL24924164 | 0.61 | — | — | |
| SCHEMBL24253708 | 0.60 | HPGD (0.37) | — | |
| SCHEMBL24253706 | 0.60 | MCL1 (0.38) | — | |
| SCHEMBL10580705 | 0.58 | ALDH1A1 (0.50) | — | |
| SCHEMBL24253401 | 0.57 | HPGD (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230009712-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-01-12 | — | — | US | disclosed |