Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 11/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 11/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24875778 | 0.90 | AKR1C3 (0.39) | AKR1C3AKR1C2PTGS1MMP8 | |
| SCHEMBL24875589 | 0.88 | AKR1C3 (0.43) | AKR1C3AKR1C2AKR1C1AKR1B10AKR1C4 | |
| SCHEMBL28719127 | 0.85 | MMP8 (0.44) | AKR1C3AKR1C2PTGS1MMP8 | |
| SCHEMBL30192923 | 0.84 | KDM4E (0.38) | AKR1C3AKR1C2PTGS1MMP8 | |
| SCHEMBL24875451 | 0.84 | KDM4E (0.38) | AKR1C3AKR1C2PTGS1MMP8 | |
| SCHEMBL24875595 | 0.84 | PTGS2 (0.44) | AKR1C3AKR1C2AKR1C1AKR1C4PTGS1 | |
| SCHEMBL20943248 | 0.83 | AKR1C3 (0.59) | AKR1C3AKR1C2AKR1C1AKR1B10AKR1C4 | |
| SCHEMBL24875421 | 0.82 | PTGS2 (0.38) | AKR1C3AKR1C2PTGS1MMP8 | |
| SCHEMBL8593582 | 0.81 | PTGS2 (0.37) | AKR1C3AKR1C2PTGS1MMP8GAA | |
| SCHEMBL24875566 | 0.80 | PAX8 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283453-A1 | PHENYL ACETAMIDE BASED IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. (US) | 2023-01-12 | — | — | WO | disclosed |