Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 6/20 | 0.59 |
| ▸ | PKM | P14618 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876355 | 0.96 | MEN1 (0.63) | MEN1KMT2ALMNAPKMMAPT | |
| SCHEMBL24876644 | 0.94 | MEN1 (0.66) | MEN1KMT2ALMNAPKMMAPT | |
| SCHEMBL31680056 | 0.89 | MEN1 (0.60) | MEN1KMT2ALMNAPKMMAPT | |
| SCHEMBL24876751 | 0.86 | LMNA (0.48) | MEN1KMT2ALMNAPKMMAPT | |
| SCHEMBL24876073 | 0.86 | LMNA (0.50) | MEN1KMT2ALMNAPKMMAPT | |
| SCHEMBL31679984 | 0.86 | MEN1 (0.62) | MEN1KMT2ALMNAPKMMAPT | |
| SCHEMBL31679985 | 0.84 | LMNA (0.69) | MEN1KMT2ALMNAPKMMAPT | |
| SCHEMBL30211038 | 0.84 | LMNA (0.56) | MEN1KMT2ALMNAPKMMAPT | |
| SCHEMBL24876204 | 0.84 | LMNA (0.56) | MEN1KMT2ALMNAPKMMAPT | |
| SCHEMBL31679978 | 0.81 | LMNA (0.65) | MEN1KMT2ALMNAPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367103-B1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-09-03 | — | — | EP | disclosed |
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |