Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | PKM | P14618 | 6/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876014 | 0.96 | MEN1 (0.62) | MEN1KMT2ALMNAPKMTHRB | |
| SCHEMBL24876644 | 0.95 | MEN1 (0.66) | MEN1KMT2ALMNAPKMTHRB | |
| SCHEMBL31680056 | 0.90 | MEN1 (0.60) | MEN1KMT2ALMNAPKMTHRB | |
| SCHEMBL31679984 | 0.87 | MEN1 (0.62) | MEN1KMT2ALMNAPKMTHRB | |
| SCHEMBL27275406 | 0.83 | LMNA (0.46) | MEN1KMT2ALMNAPKMTHRB | |
| SCHEMBL24876751 | 0.82 | LMNA (0.48) | MEN1KMT2ALMNAPKMTHRB | |
| SCHEMBL24876073 | 0.82 | LMNA (0.50) | MEN1KMT2ALMNAPKMTHRB | |
| SCHEMBL31679978 | 0.82 | LMNA (0.65) | MEN1KMT2ALMNAPKMTHRB | |
| SCHEMBL24876742 | 0.82 | PKM (0.76) | MEN1KMT2ALMNAPKMTHRB | |
| SCHEMBL31679970 | 0.81 | PKM (0.70) | MEN1KMT2ALMNAPKMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367103-B1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-09-03 | — | — | EP | disclosed |
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |