Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31679999 | 0.94 | MEN1 (0.47) | LMNASMN1; SMN2MAPTALDH1A1TP53 | |
| SCHEMBL24876073 | 0.86 | LMNA (0.50) | LMNASMN1; SMN2MAPTALDH1A1TP53 | |
| SCHEMBL24876014 | 0.86 | MEN1 (0.62) | LMNASMN1; SMN2MAPTALDH1A1TP53 | |
| SCHEMBL24876355 | 0.82 | MEN1 (0.63) | LMNASMN1; SMN2MAPTALDH1A1TP53 | |
| SCHEMBL31679934 | 0.80 | MEN1 (0.47) | LMNASMN1; SMN2MAPTALDH1A1TP53 | |
| SCHEMBL24876644 | 0.80 | MEN1 (0.66) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL24876013 | 0.80 | LMNA (0.53) | LMNASMN1; SMN2MAPTALDH1A1TP53 | |
| SCHEMBL31679866 | 0.78 | MEN1 (0.57) | LMNASMN1; SMN2MAPTALDH1A1TP53 | |
| SCHEMBL24876301 | 0.77 | MEN1 (0.47) | LMNASMN1; SMN2MAPTALDH1A1TP53 | |
| SCHEMBL24876665 | 0.77 | THRB (0.57) | LMNAMEN1KMT2APKMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367103-B1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-09-03 | — | — | EP | disclosed |
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |