Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876210 | 0.88 | FFAR4 (0.45) | MAPTMEN1KMT2AHTTTP53 | |
| SCHEMBL10954956 | 0.78 | MAPT (0.62) | MAPTMEN1KMT2AHTTTP53 | |
| SCHEMBL10958092 | 0.78 | MAPT (0.53) | MAPTMEN1KMT2AHTTTP53 | |
| SCHEMBL31236029 | 0.76 | FFAR4 (0.50) | MAPTMEN1KMT2AHTTTP53 | |
| SCHEMBL203169 | 0.72 | MAPT (0.53) | MAPTMEN1KMT2AHTTTP53 | |
| SCHEMBL14322739 | 0.72 | MAPT (0.58) | MAPTMEN1KMT2AHTTTP53 | |
| SCHEMBL30068485 | 0.70 | ALDH1A1 (0.41) | MAPTMEN1KMT2AEPHX2ALDH1A1 | |
| SCHEMBL23389142 | 0.70 | ALDH1A1 (0.41) | MAPTMEN1KMT2AEPHX2ALDH1A1 | |
| SCHEMBL24876167 | 0.70 | FFAR4 (0.47) | MAPTMEN1KMT2AHTTTP53 | |
| SCHEMBL20529653 | 0.70 | MAPT (0.49) | MAPTMEN1KMT2AHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |