Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | PKM | P14618 | 6/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | IDH1 | O75874 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876302 | 0.90 | MEN1 (0.81) | MEN1KMT2ALMNAPKMPOLB | |
| SCHEMBL24876742 | 0.86 | PKM (0.76) | MEN1KMT2ALMNAPKMPOLB | |
| SCHEMBL24876741 | 0.84 | LMNA (0.76) | MEN1KMT2ALMNAPKMPOLB | |
| SCHEMBL24876169 | 0.84 | MEN1 (0.72) | MEN1KMT2ALMNAPKMPOLB | |
| SCHEMBL24876039 | 0.84 | MEN1 (0.72) | MEN1KMT2ALMNAPKMPOLB | |
| SCHEMBL24876051 | 0.83 | PKM (0.71) | MEN1KMT2ALMNAPKMPOLB | |
| SCHEMBL31679904 | 0.83 | PKM (0.71) | MEN1KMT2ALMNAPKMPOLB | |
| SCHEMBL24876017 | 0.83 | MEN1 (0.70) | MEN1KMT2ALMNAPKMPOLB | |
| SCHEMBL24876241 | 0.82 | LMNA (0.78) | MEN1KMT2ALMNAPKMPOLB | |
| SCHEMBL24876755 | 0.82 | MEN1 (0.69) | MEN1KMT2ALMNAPKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367103-B1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-09-03 | — | — | EP | disclosed |
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |