Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4448251 | 0.95 | MAPT (0.49) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL9527232 | 0.87 | ALDH1A1 (0.50) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL14322739 | 0.87 | MAPT (0.58) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL9530670 | 0.86 | ALDH1A1 (0.49) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL2382375 | 0.84 | TDP1 (0.59) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL31237064 | 0.81 | ALDH1A1 (0.53) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL1275648 | 0.81 | ALDH1A1 (0.53) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL866003 | 0.80 | ALDH1A1 (0.62) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL29776250 | 0.80 | ALDH1A1 (0.62) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL5952155 | 0.80 | MAPT (0.53) | MAPTALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 325 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567434-A | PROTAC compound targeting CBF beta-SMMHC protein and preparation method and application thereof | 武汉大学 | 2024-02-20 | — | — | CN | claimed |
| CN-117089165-A | Multifunctional glass fiber reinforced composite material and preparation method thereof | 运城市太运建材有限公司 | 2023-11-21 | — | — | CN | claimed |
| CN-107032965-B | Preparation method of 3-trifluoromethoxyphenol | 金凯(辽宁)化工有限公司 | 2020-04-07 | — | — | CN | claimed |
| CN-107032965-A | A kind of preparation method of 3 trifluoro-methoxy-phenol | 金凯(辽宁)化工有限公司 | 2017-08-11 | — | — | CN | claimed |
| CN-1047285-A | New phenyl pyrimidine ketone derivatives and preparation method thereof | ICI PLC (GB) | 1990-11-28 | — | — | CN | claimed |
| EP-0396250-A1 | Pyrimidinone derivatives | ZENECA LIMITED (GB) | 1990-11-07 | — | — | EP | claimed |
| EP-4709712-A1 | GSK3A INHIBITORS AND METHODS OF USE THEREOF | Blueprint Medicines Corporation (US) | 2026-03-18 | — | — | EP | disclosed |
| US-20250340521-A1 | C-ABL TYROSINE KINASE INHIBITORY COMPOUND EMBODIMENTS AND METHODS OF MAKING AND USING THE SAME | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2025-11-06 | — | — | US | disclosed |
| US-12435047-B2 | c-Abl tyrosine kinase inhibitory compound embodiments and methods of making and using the same | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-10-07 | — | — | US | disclosed |
| CN-114989140-B | Benzimidazole derivatives as ERBB tyrosine kinase inhibitors for the treatment of cancer | 卡佩拉医疗公司 | 2025-03-25 | — | — | CN | disclosed |
| US-20250092028-A1 | BENZIMIDAZOLE DERIVATIVES AS ERBB TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF CANCER | CAPELLA THERAPEUTICS, INC. | 2025-03-20 | — | — | US | disclosed |
| CN-114940673-B | Benzimidazole derivatives as ERBB tyrosine kinase inhibitors for the treatment of cancer | 卡佩拉医疗公司 | 2025-03-18 | — | — | CN | disclosed |
| US-20240409533-A1 | HMOX1 INDUCERS | Astellas Engineered Small Molecules US, Incorporated | 2024-12-12 | — | — | US | disclosed |
| WO-1992006964-A1 | HETEROCYCLIC COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-30 | — | — | WO | disclosed |
| US-5109004-A | Cyano phenyl-substituted with heterocylic compound; insecticides, miticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-28 | — | — | US | disclosed |
| US-5104878-A | Insecticides, miticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-14 | — | — | US | disclosed |
| CN-1047285-A | New phenyl pyrimidine ketone derivatives and preparation method thereof | ICI PLC (GB) | 1990-11-28 | — | — | CN | disclosed |
| EP-0398499-A2 | Insecticides | ZENECA LIMITED (GB) | 1990-11-22 | — | — | EP | disclosed |
| EP-0396250-A1 | Pyrimidinone derivatives | ZENECA LIMITED (GB) | 1990-11-07 | — | — | EP | disclosed |
| EP-0063873-A1 | Haloalkoxy-substituted diphenyl ethers; their use as herbicides and in herbicidal compositions and processes of making them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12435047-B2 | c-Abl tyrosine kinase inhibitory compound embodiments and methods of making and using the same | ABL1, ABL2, MUSK | MAPT 1230/4885ALDH1A1 1314/4885MEN1 3978/4885 |
| US-20250340521-A1 | C-ABL TYROSINE KINASE INHIBITORY COMPOUND EMBODIMENTS AND METHODS OF MAKING AND USING THE SAME | ABL1, ABL2, MUSK | MAPT 1230/4885ALDH1A1 1314/4885MEN1 3978/4885 |
| US-20240409533-A1 | HMOX1 INDUCERS | HMOX1, HMOX2, HMBS | MAPT 3846/4885ALDH1A1 332/4885MEN1 2693/4885 |
| US-20250092028-A1 | BENZIMIDAZOLE DERIVATIVES AS ERBB TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF CANCER | ERBB2, ERBB4, ERBB3 | MAPT 3898/4885ALDH1A1 1250/4885MEN1 3595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.