Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 6/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31679874 | 1.00 | LMNA (0.53) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL31679979 | 0.88 | LMNA (0.65) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL31679997 | 0.78 | LMNA (0.57) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL24876095 | 0.77 | LMNA (0.69) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL24876646 | 0.77 | LMNA (0.65) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL24876221 | 0.77 | LMNA (0.53) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL31679808 | 0.77 | LMNA (0.53) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL24876257 | 0.75 | LMNA (0.54) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL31680057 | 0.75 | LMNA (0.54) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL24876204 | 0.75 | LMNA (0.56) | LMNAMEN1KMT2APKMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |