Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 5/20 | 0.61 |
| ▸ | THRB | P10828 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876656 | 0.98 | LMNA (0.65) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL31679802 | 0.85 | LMNA (0.55) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL24876661 | 0.85 | LMNA (0.46) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL24876241 | 0.82 | LMNA (0.78) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL24876742 | 0.80 | PKM (0.76) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL24876095 | 0.79 | LMNA (0.69) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL24876753 | 0.79 | LMNA (1.00) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL24876174 | 0.79 | MEN1 (1.00) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL24876741 | 0.78 | LMNA (0.76) | LMNAMEN1KMT2APKMTHRB | |
| SCHEMBL24876169 | 0.78 | MEN1 (0.72) | LMNAMEN1KMT2APKMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367103-B1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-09-03 | — | — | EP | disclosed |
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |