Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 5/20 | 0.56 |
| ▸ | THRB | P10828 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GBA1 | P04062 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31679936 | 1.00 | LMNA (0.63) | LMNAMAPTPOLBTHRBMEN1 | |
| SCHEMBL31679842 | 0.98 | LMNA (0.63) | LMNAMAPTPOLBTHRBMEN1 | |
| SCHEMBL31679964 | 0.94 | LMNA (0.60) | LMNAMAPTPOLBTHRBMEN1 | |
| SCHEMBL24876074 | 0.94 | LMNA (0.60) | LMNAMAPTPOLBTHRBMEN1 | |
| SCHEMBL31679833 | 0.92 | LMNA (0.50) | LMNAMAPTPOLBTHRBMEN1 | |
| SCHEMBL24876599 | 0.89 | LMNA (0.48) | LMNAMAPTPOLBTHRBMEN1 | |
| SCHEMBL31679983 | 0.89 | LMNA (0.48) | LMNAMAPTPOLBTHRBMEN1 | |
| SCHEMBL24876045 | 0.86 | LMNA (0.66) | LMNAMAPTPOLBTHRBMEN1 | |
| SCHEMBL30210931 | 0.86 | LMNA (0.66) | LMNAMAPTPOLBTHRBMEN1 | |
| SCHEMBL24876600 | 0.86 | LMNA (0.69) | LMNAMAPTPOLBTHRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |