Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31679936 | 0.92 | LMNA (0.63) | LMNAMAPTPOLBKMT2AMEN1 | |
| SCHEMBL24876379 | 0.92 | LMNA (0.63) | LMNAMAPTPOLBKMT2AMEN1 | |
| SCHEMBL31679983 | 0.92 | LMNA (0.48) | LMNAMAPTPOLBKMT2AMEN1 | |
| SCHEMBL24876599 | 0.92 | LMNA (0.48) | LMNAMAPTPOLBKMT2AMEN1 | |
| SCHEMBL31679842 | 0.90 | LMNA (0.63) | LMNAMAPTPOLBKMT2AMEN1 | |
| SCHEMBL24876074 | 0.86 | LMNA (0.60) | LMNAMAPTPOLBKMT2AMEN1 | |
| SCHEMBL31679964 | 0.86 | LMNA (0.60) | LMNAMAPTPOLBKMT2AMEN1 | |
| SCHEMBL24876608 | 0.85 | LMNA (0.54) | LMNAMAPTPOLBKMT2AMEN1 | |
| SCHEMBL31679945 | 0.85 | LMNA (0.54) | LMNAMAPTPOLBKMT2AMEN1 | |
| SCHEMBL24876372 | 0.84 | LCK (0.45) | LMNAMAPTPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367103-B1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-09-03 | — | — | EP | disclosed |