Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 6/20 | 0.48 |
| ▸ | GBA1 | P04062 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876074 | 1.00 | LMNA (0.60) | LMNAPOLBMAPTMEN1KMT2A | |
| SCHEMBL31679842 | 0.94 | LMNA (0.63) | LMNAPOLBMAPTMEN1KMT2A | |
| SCHEMBL31679936 | 0.94 | LMNA (0.63) | LMNAPOLBMAPTMEN1KMT2A | |
| SCHEMBL24876379 | 0.94 | LMNA (0.63) | LMNAPOLBMAPTMEN1KMT2A | |
| SCHEMBL31679833 | 0.86 | LMNA (0.50) | LMNAPOLBMAPTMEN1KMT2A | |
| SCHEMBL24876045 | 0.84 | LMNA (0.66) | LMNAPOLBMAPTMEN1KMT2A | |
| SCHEMBL30210931 | 0.84 | LMNA (0.66) | LMNAPOLBMAPTMEN1KMT2A | |
| SCHEMBL24876064 | 0.83 | LMNA (0.69) | LMNAPOLBMAPTMEN1KMT2A | |
| SCHEMBL24876600 | 0.83 | LMNA (0.69) | LMNAPOLBMAPTMEN1KMT2A | |
| SCHEMBL31679839 | 0.83 | LMNA (0.69) | LMNAPOLBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367103-B1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-09-03 | — | — | EP | disclosed |