Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 6/20 | 0.64 |
| ▸ | THRB | P10828 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | PKLR | P30613 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876096 | 0.85 | LMNA (0.57) | LMNAKMT2AMEN1PKMTHRB | |
| SCHEMBL24876161 | 0.85 | KMT2A (0.55) | LMNAKMT2AMEN1PKMTHRB | |
| SCHEMBL24876241 | 0.84 | LMNA (0.78) | LMNAKMT2AMEN1PKMTHRB | |
| SCHEMBL24876245 | 0.83 | LMNA (0.60) | LMNAKMT2AMEN1PKMTHRB | |
| SCHEMBL24876620 | 0.83 | LMNA (0.60) | LMNAKMT2AMEN1PKMTHRB | |
| SCHEMBL24876755 | 0.83 | MEN1 (0.69) | LMNAKMT2AMEN1PKMTHRB | |
| SCHEMBL27275411 | 0.82 | BRD4 (0.52) | LMNAKMT2AMEN1PKMTHRB | |
| SCHEMBL24876594 | 0.82 | LMNA (0.65) | LMNAKMT2AMEN1PKMTHRB | |
| SCHEMBL24876742 | 0.82 | PKM (0.76) | LMNAKMT2AMEN1PKMTHRB | |
| SCHEMBL31680059 | 0.81 | LMNA (0.63) | LMNAKMT2AMEN1PKMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367103-B1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-09-03 | — | — | EP | disclosed |
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |