Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | BRD4 | O60885 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876096 | 0.85 | LMNA (0.57) | KMT2ABRD4PKMLMNASMN1; SMN2 | |
| SCHEMBL24876754 | 0.85 | LMNA (0.67) | KMT2ABRD4PKMLMNASMN1; SMN2 | |
| SCHEMBL24876746 | 0.83 | ACLY (0.56) | KMT2APKMLMNATHRBMEN1 | |
| SCHEMBL31679882 | 0.80 | LMNA (0.51) | KMT2APKMLMNASMN1; SMN2MAPT | |
| SCHEMBL24876371 | 0.80 | LMNA (0.51) | KMT2APKMLMNASMN1; SMN2MAPT | |
| SCHEMBL24876630 | 0.79 | LMNA (0.54) | BRD4PKMLMNATHRB | |
| SCHEMBL31680050 | 0.79 | PKM (0.54) | KMT2APKMLMNATHRBMEN1 | |
| SCHEMBL31680027 | 0.79 | LMNA (0.54) | KMT2ABRD4PKMLMNATHRB | |
| SCHEMBL24876611 | 0.79 | PKM (0.54) | KMT2APKMLMNATHRBMEN1 | |
| SCHEMBL31680063 | 0.79 | LMNA (0.54) | BRD4PKMLMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367103-B1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-09-03 | — | — | EP | disclosed |
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |